Corneal Layer Thickness Mapping With Optical Coherence Tomography in Different Stages Reveals Pathologic Processes of Keratoconus
Corneal layer thickness mapping using swept-source optical coherence tomography in a 10-mm diameter cornea across various severities of KC, from very mild to advanced, revealed that epithelial and stromal thicknesses changed with KC severity and was involved in the pathogenesis of KC progression. Pathological changes in the stroma may precede those in the epithelium. Epithelial compensatory mechanisms in clinical and topographic KC may not have fully emerged in VAE-NT.
Authors
- Sayo Maeno (ORCID: https://orcid.org/0000-0002-0301-6775)
- Kohji Nishida (ORCID: https://orcid.org/0000-0001-9069-3610)
- Shizuka Koh (ORCID: https://orcid.org/0000-0002-5402-3051)
- Bernardo T. Lopes (ORCID: https://orcid.org/0000-0002-8489-3621)
- Renato Ambrósio (ORCID: https://orcid.org/0000-0001-6919-4606)
- Naoyuki Maeda (ORCID: https://orcid.org/0000-0001-6509-9054)
- Ryota Inoue (ORCID: https://orcid.org/0009-0002-5573-5920)
- Risako Matsuo
Institutions
- University of Liverpool (GB)
- Alder Hey Children's Hospital (GB)
- Universidade Federal do Estado do Rio de Janeiro (BR)
- The University of Osaka (JP)
Publication Details
- Journal
- Cornea
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1097/ico.0000000000003693
- Citations
- 3
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.21
Funders
- Science for Equity, Empowerment and Development Division