Drug induced lupus associated with Trastuzumab emtansine in a patient with metastatic breast cancer

Drug-induced lupus is a clinical syndrome that shares similar features with systemic lupus erythematosus (SLE). The majority of patients present with symptoms such as arthralgia and myalgia. Hydralazine and procainamide are high-risk drugs for drug-induced lupus. Symptoms usually develop after months or years of use, but may also develop suddenly. Our patient also received TDM-1 treatment for 18 months. We present a case of TDM-1-associated drug-induced lupus in a patient with metastatic breast cancer. This is the first case of TDM-1-related drug-induced lupus reported in the literature.

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Publication Details

Journal
Journal of Oncology Pharmacy Practice
Published
2024-09-23
DOI
https://doi.org/10.1177/10781552241276191
Citations
1
Primary Topic
HER2/EGFR in Cancer Research
Type
article
Field-Weighted Citation Impact
0.28
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article

Drug induced lupus associated with Trastuzumab emtansine in a patient with metastatic breast cancer

Talat Aykut, Özlem Şahin, Zeliha Çelik, Mehmet Artaç et al.
1 citations
Journal of Oncology Pharmacy Practice
HER2/EGFR in Cancer Research
0.28
article

Drug induced lupus associated with Trastuzumab emtansine in a patient with metastatic breast cancer

Talat Aykut, Özlem Şahin, Zeliha Çelik, Mehmet Artaç, Murat Araz, Melek Karakurt Eryılmaz, Oğuzhan Yıldız, Ali Fuat Gürbüz, Naciye Hilal Büyükboyacı
article en
1 citations

Abstract

Drug-induced lupus is a clinical syndrome that shares similar features with systemic lupus erythematosus (SLE). The majority of patients present with symptoms such as arthralgia and myalgia. Hydralazine and procainamide are high-risk drugs for drug-induced lupus. Symptoms usually develop after months or years of use, but may also develop suddenly. Our patient also received TDM-1 treatment for 18 months. We present a case of TDM-1-associated drug-induced lupus in a patient with metastatic breast cancer. This is the first case of TDM-1-related drug-induced lupus reported in the literature.

Journal of Oncology Pharmacy PracticeVol. 31(1)
Necmettin Erbakan University (TR)
Openalex Percentile: Top 36%
HER2/EGFR in Cancer Research
0.28
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