Clinical effects of CYP2D6 phenoconversion in patients with psychosis

Polypharmacy and phenoconversion were prevalent and accounted for a significant increase in PMs. CYP2D6 may play a limited role in side effects, symptoms and well-being measures. However, due to the high frequency of occurrence, phenoconversion should be considered in future clinical trials.

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Publication Details

Journal
Journal of Psychopharmacology
Published
2024-09-23
DOI
https://doi.org/10.1177/02698811241278844
Citations
2
Primary Topic
Schizophrenia research and treatment
Type
article
Field-Weighted Citation Impact
0.77

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article

Clinical effects of CYP2D6 phenoconversion in patients with psychosis

Roos van Westrhenen, Thérèse van Amelsvoort, Emma Y De Brabander, Esmee Breddels
2 citations
Journal of Psychopharmacology
Schizophrenia research and treatment
0.77
article

Clinical effects of CYP2D6 phenoconversion in patients with psychosis

Roos van Westrhenen, Thérèse van Amelsvoort, Emma Y De Brabander, Esmee Breddels
article en
2 citations

Abstract

Polypharmacy and phenoconversion were prevalent and accounted for a significant increase in PMs. CYP2D6 may play a limited role in side effects, symptoms and well-being measures. However, due to the high frequency of occurrence, phenoconversion should be considered in future clinical trials.

Journal of PsychopharmacologyVol. 38(12)
Radboud University Nijmegen (NL), King's College London (GB), Radboud University Medical Center (NL), Maastricht University (NL), Parnassia Groep (NL), St. John's National Academy of Health Sciences (IN)
Horizon 2020 Framework Programme
Openalex Percentile: Top 26%
Schizophrenia research and treatment
0.77
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