Influence of panic disorder and paroxetine on brain functional hubs in drug-free patients

Patients with PD exhibited abnormal DC and FC, notably in the limbic network, temporal, and occipital regions. Paroxetine ameliorated patients' symptoms while altering their brain FC. SVM and SVR models, utilizing baseline DC, effectively distinguished the patients from HCs and accurately predicted TR.

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Publication Details

Journal
Journal of Psychopharmacology
Published
2024-09-23
DOI
https://doi.org/10.1177/02698811241278780
Primary Topic
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Type
article
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article

Influence of panic disorder and paroxetine on brain functional hubs in drug-free patients

Wenbin Guo, Xiaoxiao Shan, Haohao Yan, Yiding Han et al.
Journal of Psychopharmacology
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
article

Influence of panic disorder and paroxetine on brain functional hubs in drug-free patients

Wenbin Guo, Xiaoxiao Shan, Haohao Yan, Yiding Han, Yingying Zhang, Ping Li, Huabing Li, Jingping Zhao, Feng Liu
article en

Abstract

Patients with PD exhibited abnormal DC and FC, notably in the limbic network, temporal, and occipital regions. Paroxetine ameliorated patients' symptoms while altering their brain FC. SVM and SVR models, utilizing baseline DC, effectively distinguished the patients from HCs and accurately predicted TR.

Journal of PsychopharmacologyVol. 38(12)
Central South University (CN), Tianjin Medical University General Hospital (CN), Second Xiangya Hospital of Central South University (CN), Qiqihar Medical University (CN)
Good health and well-being
Openalex Percentile: Top 80%
Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
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