Patterns and Frequency of Pathogenic Germline Variants Among Prostate Cancer Patients Utilizing Multi-Gene Panel Genetic Testing
This study is the first to characterize the germline genetic profile of an Arab population with PCa. All detected P/LPGVs were potentially actionable, with most variants able to be detected with a PCa-specific panel.
Authors
- Edward D. Esplin (ORCID: https://orcid.org/0000-0001-9205-3756)
- Yosra Al-Masri
- Hikmat Abdel‐Razeq (ORCID: https://orcid.org/0000-0003-2833-6051)
- Sarah M. Nielsen (ORCID: https://orcid.org/0000-0002-5916-6393)
- Ramiz Abu‐Hijlih (ORCID: https://orcid.org/0000-0001-5397-6267)
- Hira Bani Hani (ORCID: https://orcid.org/0009-0001-3604-0886)
- Brandie Heald (ORCID: https://orcid.org/0000-0003-4227-3675)
- Baha’ Sharaf (ORCID: https://orcid.org/0000-0003-4368-1224)
- Abdulla Alzibdeh (ORCID: https://orcid.org/0000-0002-4962-8398)
- Rami Ghanem (ORCID: https://orcid.org/0009-0006-8347-0658)
- Tamer Al-Batsh
- Samer Salah (ORCID: https://orcid.org/0000-0002-9843-4784)
Institutions
- University of Jordan (JO)
- King Hussein Cancer Center (JO)
- Invitae (United States) (US)
Publication Details
- Journal
- World Journal of Oncology
- Published
- 2024-09-23
- DOI
- https://doi.org/10.14740/wjon1896
- Citations
- 3
- Primary Topic
- Nutrition, Genetics, and Disease
- Type
- article
- Field-Weighted Citation Impact
- 1.65