Systems pharmacology-based drug discovery from Amaryllidaceae alkaloids and investigation of mechanisms of action in treatment of Alzheimer’s disease
This study explained the mechanisms of Amaryllidaceae alkaloids in preventing and treating Alzheimer's disease and established a novel strategy to discover new drugs from biological chemical sources.
Authors
- Jialiang Chen (ORCID: https://orcid.org/0000-0001-8586-6839)
- Dan Qu (ORCID: https://orcid.org/0000-0001-7075-2505)
- Yan Ding (ORCID: https://orcid.org/0000-0001-8431-7694)
- Wei Li (ORCID: https://orcid.org/0000-0003-4143-8597)
- Ming Li (ORCID: https://orcid.org/0000-0002-4923-1964)
- Jianing Li (ORCID: https://orcid.org/0000-0002-0143-8894)
- Lin Zhu (ORCID: https://orcid.org/0000-0002-6050-7773)
- Shuhong Ye (ORCID: https://orcid.org/0000-0003-2581-1777)
Institutions
- Dalian Medical University (CN)
- Korea Institute of Oriental Medicine (KR)
- Shenyang Jianzhu University (CN)
- Dalian Polytechnic University (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2024-09-21
- DOI
- https://doi.org/10.1093/jpp/rgae113
- Primary Topic
- Chemical synthesis and alkaloids
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Liaoning Province