Stereoselective Construction of the ABCDE Pentacyclic Motif of Phainanoids via Norrish–Yang Photocyclization Reaction
A Norrish-Yang photocyclization reaction has been applied to regio- and stereoselective construction of the ABCDE pentacyclic motif of natural product phainanoids. The observed substrate conformation control implicates this powerful reaction could be applied to the construction of structurally diverse natural product scaffolds.
Authors
- Hao-Yuan Liu
- Zhen Jun Yang (ORCID: https://orcid.org/0000-0001-8036-934X)
- Yuanhe Li (ORCID: https://orcid.org/0000-0003-2128-5634)
- Zhongchao Zhang (ORCID: https://orcid.org/0000-0001-5017-5691)
- Zhenyu Zhang (ORCID: https://orcid.org/0000-0002-2187-9494)
- Jiahua Chen (ORCID: https://orcid.org/0000-0002-6405-816X)
- Yi-Ke Zhou
Institutions
- Peking University (CN)
- Shenzhen Bay Laboratory (CN)
- Beijing National Laboratory for Molecular Sciences (CN)
- Center for Life Sciences (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1021/acs.orglett.4c02411
- Citations
- 6
- Primary Topic
- Synthesis of Indole Derivatives
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- Peking University
- Shenzhen-Hong Kong Institute of Brain Science