Physicochemical Analysis in Standardization of Siddha Herbal Drug Kanduparangi Ver Chooranam (KVC)

Introduction: Tamil Nadu, South India, is home to an antiquated Siddha system of medicine.Siddha medicines arrest the body's cells from ageing.The word "Marunthu" (drug) itself refers to scented roots or leaves in Tamil literature.Siddhars who were the pioneers of the Siddha system have been writing down the formulation of numerous remedies since ancient times.Among those formulations, Kanduparangi Ver Chooranam (kvc) is one of the herbal formulation, which is said to be prescribed for sinusitis in classical siddha texts.Sinusitis is an infection of the sinuses.These infections usually happen after a cold or with allergies.Frontal sinus begins to grow after birth as nasofrontal ducts whereas maxillary, ethmoidal and sphenoidal sinuses are present right at birth.Sinusitis can be classified as either acute or chronic.The ethmoid and maxillary sinuses are the earliest to develop in paediatric sinusitis.In recent times, among people, there has been a positive ray of hope in getting treatment from Siddha for sinusitis also.KVC was standardized using PLIM criteria, which were crucial to the process of Occidentalizing.Material and methods: KVC was made in accordance with GMP regulations.Physio-chemical analysis, HPTLC, TLC investigation, and the finding of organoleptic qualities are all part of drug standardization.The investigation was conducted at Noble Research Solution's facility in accordance with PLIM criteria.Results: Research findings indicate there are ten peaks in the HPTLC screening graphic.Other characteristics include loss of drying (8.06 %), total ash value (2.16%), acid insoluble ash (0.14%), water soluble extraction (18.77 %), alcohol soluble extraction (8.06 %), and pH (6.0) which is weakly acidic.Conclusion: Future clinical research and standardization would benefit from the published data.