2024 ACVIM Forum Research Report Program

BACKGROUND: Right-sided heart disease (RHD) results in systemic venous hypertension.The clinical impact of elevated venous pressures on gastrointestinal health is unknown.HYPOTHESIS: Measures of gastrointestinal dysfunction increase with increasing severity of RHD.ANIMALS: Eighteen dogs with RHD: compensated RHD without hepatic venous dilation (Group 1), compensated RHD with hepatic venous dilation (Group 2), and decompensated RHD with ascites (Group 3).METHODS: Prospective clinical trial.All dogs had a comprehensive echocardiogram performed, including evaluation of hepatic/caval vein distension and collapsibility.Beyond conventional hematologic, fecal, and urine testing, thromboelastography, N-terminal pro-B-type natriuretic peptide (NT-proBNP), C-reactive protein (CRP), cobalamin, folate, methylmalonic acid (MMA), and serum intestinal fatty acid-Laurent Couetil Omega-3 Polyunsaturated Fatty Acids Supplementation Modulates Airway Response to Dust Exposure in Thoroughbred Racehorses