Melatonin alleviates high glucose-induced cardiomyocyte injury through suppressing mitochondrial FUNDC1-DRP1 axis
Hyperglycemia induced mitochondrial fragmentation and altered electron transport chain complex functions, which could be ameliorated by MEL treatment, suggesting its potential as a cardiovascular therapeutic.
Authors
- Lili Zhao (ORCID: https://orcid.org/0000-0002-6366-8206)
- Wenbin He (ORCID: https://orcid.org/0000-0002-9372-052X)
- Jixiang Wang
- Junyi Zheng (ORCID: https://orcid.org/0000-0002-0170-9658)
- Xukun Guo (ORCID: https://orcid.org/0009-0009-2968-8172)
- Yingying Zhang (ORCID: https://orcid.org/0009-0008-0207-1490)
Institutions
- Tianjin University (CN)
- Tianjin Infectious Diseases Hospital (CN)
- Tianjin Chest Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Journal of Pharmacy and Pharmacology
- Published
- 2024-09-22
- DOI
- https://doi.org/10.1093/jpp/rgae114
- Citations
- 5
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 2.86