Discovery of new pesticide candidates from nature: design, synthesis and bioactivity research of rutaecarpine derivatives
The natural product rutaecarpine and its derivatives were synthesized, and evaluated for their anti-TMV and fungicidal activities. Compounds 5n and 5p with good activities emerged as new antiviral and anti-fungal candidates, respectively. This study provides important information for the research and development of the novel antiviral and fungicidal agents based on rutaecarpine derivatives. © 2024 Society of Chemical Industry.
Authors
- Taiqing Li
- Zhenghong Zhou (ORCID: https://orcid.org/0000-0001-7753-4236)
- Aidang Lu (ORCID: https://orcid.org/0000-0002-2255-8828)
- Qingmin Wang (ORCID: https://orcid.org/0000-0002-6062-3766)
- Ziwen Wang (ORCID: https://orcid.org/0000-0001-9798-7021)
- Miaomiao Chen (ORCID: https://orcid.org/0000-0002-4866-8072)
- Xingxing He (ORCID: https://orcid.org/0000-0003-0495-6897)
- Xin Guo
- Xing‐chen Hang
- De‐ya Wen
Institutions
- Tianjin Normal University (CN)
- Hebei University of Technology (CN)
- Nankai University (CN)
Publication Details
- Journal
- Pest Management Science
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1002/ps.8430
- Citations
- 2
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.50
Funders
- National Key Research and Development Program of China