Theophylline use—a conundrum in modern medicine: a case report

Theophylline is a methylxanthine derivative medication that is used sparingly in the treatment of airway diseases. It has become less favorable over the years due to its narrow therapeutic index and potential for development of toxicity. Monitoring serum drug levels and adjusting the dose frequently to maintain a therapeutic range is essential to prevent toxicity related to theophylline. There is emerging evidence that the drug might have anti-inflammatory properties to aid in treating many chronic airway disorders and pharmacovigilance is necessary for its continued use.

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Publication Details

Journal
AME Case Reports
Published
2024-09-23
DOI
https://doi.org/10.21037/acr-24-111
Citations
1
Primary Topic
Pharmacology and Obesity Treatment
Type
article
Field-Weighted Citation Impact
0.45
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article

Theophylline use—a conundrum in modern medicine: a case report

Subramanya Shyam Ganti, Jayaramakrishna Depa, Dedeepya Gullapalli, S.S. Kommineni et al.
1 citations
AME Case Reports
Pharmacology and Obesity Treatment
0.45
article

Theophylline use—a conundrum in modern medicine: a case report

Subramanya Shyam Ganti, Jayaramakrishna Depa, Dedeepya Gullapalli, S.S. Kommineni, Tara Rahmlow
article en
1 citations

Abstract

Theophylline is a methylxanthine derivative medication that is used sparingly in the treatment of airway diseases. It has become less favorable over the years due to its narrow therapeutic index and potential for development of toxicity. Monitoring serum drug levels and adjusting the dose frequently to maintain a therapeutic range is essential to prevent toxicity related to theophylline. There is emerging evidence that the drug might have anti-inflammatory properties to aid in treating many chronic airway disorders and pharmacovigilance is necessary for its continued use.

AME Case ReportsVol. 9
Appalachian Regional Healthcare (US)
Zero hunger
Openalex Percentile: Top 31%
Pharmacology and Obesity Treatment
0.45
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