Tumor immune microenvironment analysis of non-small cell lung cancer development through multiplex immunofluorescence
This study offers an in-depth analysis of immune changes in NSCLC, demonstrating that the transition from AIS/MIA to invasive stage I NSCLC leads to immune activation, while the advancement from stage I to stage III cancer results in immune suppression. These findings contribute to our understanding of the molecular mechanisms underlying early-stage NSCLC progression and pave the way for the identification of potential treatment options.
Authors
- Zhaofeng Wang (ORCID: https://orcid.org/0000-0002-0547-8172)
- Yucheng Lu (ORCID: https://orcid.org/0000-0003-1510-9351)
- Mengli Huang (ORCID: https://orcid.org/0000-0003-0169-7906)
- Jinping Cai
- Honggang Ke
- Yong Song (ORCID: https://orcid.org/0000-0003-2391-5820)
- Junling Zhang
- Haiying Wang (ORCID: https://orcid.org/0000-0002-1593-0708)
- Ding Zhang (ORCID: https://orcid.org/0000-0002-1876-5090)
- Jiaping Zhao (ORCID: https://orcid.org/0000-0002-2054-6989)
- K Patel (ORCID: https://orcid.org/0000-0002-4066-3103)
- Bei Zhang
- Andreas Pircher
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Hua Medicine (China) (CN)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Translational Lung Cancer Research
- Published
- 2024-09-01
- DOI
- https://doi.org/10.21037/tlcr-24-379
- Citations
- 6
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Massachusetts Department of Agricultural Resources