Curcumin promotes ferroptosis in hepatocellular carcinoma via upregulation of ACSL4
This study showed that curcumin significantly decreased the proliferation of HCC cells and significantly increased the sensitivity of ferroptosis. These results suggest that ACSL4 is a viable target for curcumin-induced ferroptosis in treating HCC.
Authors
- Yongxin Yu
- Mingyu Sun (ORCID: https://orcid.org/0000-0001-8103-7283)
- Dengcheng Hui
- Yulang Jiang
- Xiaofan Yu (ORCID: https://orcid.org/0000-0001-9665-7805)
- Chao Wu (ORCID: https://orcid.org/0000-0003-0260-2868)
- Lu Liu (ORCID: https://orcid.org/0000-0002-7496-5564)
- Ziyang Pan
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2024-09-23
- DOI
- https://doi.org/10.1007/s00432-024-05878-0
- Citations
- 28
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 11.73