Gut microbiota and functional outcome after ischemic stroke: a Mendelian randomization study
This study provides genetic support that the gut microbiota, especially those associated with short-chain fatty acids, could affect stroke prognosis by mediating synapse function. Our findings suggest that modifying the composition of the gut microbiota could improve the prognosis of ischemic stroke.
Authors
- Dian Qu
- Guichun Yang
- Deming Jiang (ORCID: https://orcid.org/0000-0003-1748-0293)
- Linlin Wang (ORCID: https://orcid.org/0000-0002-2231-6642)
- Huan Liang (ORCID: https://orcid.org/0009-0008-5126-5144)
- Yan Xin
Institutions
- Harbin Medical University (CN)
- Capital Medical University (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang Provincial Hospital (CN)
- Shenyang 242 Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1414653
- Citations
- 10
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 2.34
Funders
- Health Commission of Heilongjiang Province