Distinct soluble immune checkpoint profiles characterize COVID-19 severity, mortality and SARS-CoV-2 variant infections
Of importance, this study provides a comprehensive analysis of circulatory immune factors governing the COVID-19 pathology, and identifies key roles of sCD40, sTIM-1, and Galectin-9 in predicting mortality.
Authors
- Ionela-Larisa Miftode (ORCID: https://orcid.org/0000-0003-4131-1019)
- Claudia Plesca (ORCID: https://orcid.org/0009-0002-5704-578X)
- Mariana Pavel-Tanasă (ORCID: https://orcid.org/0000-0002-2802-5993)
- Tudorița Gabriela Părângă (ORCID: https://orcid.org/0000-0002-8404-2771)
- Egidia Miftode (ORCID: https://orcid.org/0000-0002-8644-095X)
- Petru Cianga (ORCID: https://orcid.org/0000-0002-5403-2265)
- Elena Iftimi
- Daniela Constantinescu (ORCID: https://orcid.org/0000-0003-0732-3745)
Institutions
- Clinical Emergency Hospital Bucharest (RO)
- Grigore T. Popa University of Medicine and Pharmacy (RO)
- Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi (RO)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-23
- DOI
- https://doi.org/10.3389/fimmu.2024.1464480
- Citations
- 8
- Primary Topic
- COVID-19 Clinical Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.11
Funders
- Universitatea de Medicina și Farmacie Grigore T. Popa - Iasi
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii