Intracholecystic Papillary Neoplasm: A Rare Case Report

Intracholecystic papillary neoplasm (ICPN) is a mass-forming, noninvasive epithelial premalignant neoplasm arising from the gallbladder mucosal lining and projecting into the lumen of the gallbladder. It is potentially fatal and if left untreated can progress to invasive gallbladder carcinoma. Incidentally ICPN is found on imaging or during postoperative histological evaluation and is likely to be missed preoperatively. We present a rare case of ICPN in a 70-year-old female patient who was admitted with complaints of pain in the right hypochondrium since one month and was postoperatively diagnosed with ICPN through histopathological examination. We discuss the need for early intervention in gallbladder polypoidal masses to prevent the conversion of benign or preinvasive tumors to malignancy.