<scp>KA</scp>‐mediated excitotoxicity induces neuronal ferroptosis through activation of ferritinophagy
KA-induced excitotoxicity activates ferritinophagy, and targeting ferritinophagy effectively inhibits downstream ferroptosis. Interference with NCOA4 effectively attenuates KA-induced neuronal damage. This study provides a potential therapeutic target for excitotoxicity related disease conditions.
Authors
- Zheng‐Hong Qin
- Yi‐Yue Jiang
- Yan Wang (ORCID: https://orcid.org/0000-0001-7764-8233)
- Jing Wang (ORCID: https://orcid.org/0000-0002-3224-3993)
- Na Liu (ORCID: https://orcid.org/0000-0003-3832-5591)
- Xiaorui Wan
- Jiani Huang (ORCID: https://orcid.org/0000-0003-3796-0737)
- Weilong Wu
Institutions
- Soochow University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/cns.70054
- Citations
- 10
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.19
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province