Regional lymph node changes on breast MRI in patients with early-stage breast cancer receiving neoadjuvant chemo-immunotherapy
The combination of neoadjuvant paclitaxel and pembrolizumab ± SD101 intratumoral injection was associated with early increases in regional lymphadenopathy on MRI despite decreased breast tumor size. Increased lymphadenopathy was not associated with node positive disease at surgery.
Authors
- Michelle Melisko (ORCID: https://orcid.org/0000-0002-8729-4667)
- Rita Nanda (ORCID: https://orcid.org/0000-0001-5248-0876)
- Anika Christofferson
- Rita A. Mukhtar (ORCID: https://orcid.org/0000-0001-8079-7846)
- Hongmei Yu (ORCID: https://orcid.org/0000-0002-9852-2485)
- A. Jo Chien (ORCID: https://orcid.org/0000-0003-2978-6249)
- Samantha Fisch
- Melanie Majure
- Laura J. Esserman (ORCID: https://orcid.org/0000-0001-9202-4568)
- Elissa R. Price (ORCID: https://orcid.org/0000-0001-9572-7795)
- Gillian L. Hirst (ORCID: https://orcid.org/0000-0002-4502-0035)
- Saya Jacob (ORCID: https://orcid.org/0000-0002-9311-5303)
- Hope S. Rugo (ORCID: https://orcid.org/0000-0001-6710-4814)
- Hatem Soliman (ORCID: https://orcid.org/0000-0001-6644-2264)
- Peter Norwood
- Paolo Castillo
- Cheryl Ewing
Institutions
- Moffitt Cancer Center (US)
- University of California San Diego (US)
- University of Chicago (US)
- Quantum Leap Healthcare Collaborative (US)
- UCSF Helen Diller Family Comprehensive Cancer Center (US)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2024-09-21
- DOI
- https://doi.org/10.1007/s10549-024-07481-w
- Citations
- 4
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.13
Funders
- University of California, San Francisco