Abstract A083 Ethnic disparities in esophageal cancer across New York State

Abstract Introduction Esophageal cancer is one of the most fatal cancers in the United States. Moreover, disparities in mortality, or incidence rates of esophageal cancer have been reported. Here, we conducted a retrospective study to investigate disparities in esophageal cancer in the state of New York. Method Mortality and 5-year survival rate were analyzed through Surveillance, Epidemiology, and End Results (SEER) Stat Database (1969-2022). Mortality and survival data were analyzed by counties in the state of New York. The 5-year survival was analyzed through the Kaplan-Meier curve and SEER combined staging and ethnicity (non-hispanic white; NHW, non-hispanic black; NHB, Asians/Pacific Islanders; API, and Hispanics). Result Bronx County revealed the highest mortality rate among New York City Counties (5.6 per 100,000, 95% CI, 5.4-5.8), and Queens County showed the lowest mortality. (3.9 per 100,000, 95% CI, 3.7-4.0). In localized esophageal cancer, one year survival was highest in the NHW (79.3%, 95% CI, 75.9- 82.2%) in New York, whereas 2-5 year survival rates were highest in the NHB (52.0%, 47.3%, 40.2%, and 38.4%, respectively). Hispanics showed the lowest survival rate in the localized stage. In comparison, API showed the highest survival (1-5 year survival 46.8%, 29.6%, 16.8%, 13.3%, and 12.1% respectively) and NHB revealed the lowest survival outcome in distant metastatic esophageal cancer (1-5 year survival 28.8%, 13.5%, 8.1%, 5.9%, and 5.1% respectively) throughout 5 years. Conclusion Mortality and 5 year survival rates varied across the boroughs of New York City. Early intervention and primary prevention could be especially beneficial in the Bronx, where targeted efforts could help prevent patients from advancing to the distant metastatic stage, considering the unique demographics and healthcare disparities in this area. Citation Format: Inae Park, Sungjae Park, Misuk Lee. Ethnic disparities in esophageal cancer across New York State [abstract]. In: Proceedings of the 17th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2024 Sep 21-24; Los Angeles, CA. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2024;33(9 Suppl):Abstract nr A083.