Rare Presentation of Testicular Cancer With Malignant Tumor Thrombus: A Case Report

In rare cases, testicular cancer can metastasize to the inferior vena cava (IVC) through a tumor thrombus, significantly worsening the prognosis. This case report describes the management and the outcome of a rare presentation of testicular cancer. A 38-year-old male presented with a testicular mass and was found to have a mixed germ cell tumor with predominantly yolk sac components. Imaging after the initial orchiectomy revealed an IVC tumor thrombus extending from the left renal vein, as well as retroperitoneal and pulmonary metastases. The patient was urgently started on anticoagulation and underwent three cycles of BEP chemotherapy (bleomycin, etoposide, and cisplatin), which led to complete metabolic and radiographic regression of the metastatic disease.

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Publication Details

Journal
Cureus
Published
2024-09-21
DOI
https://doi.org/10.7759/cureus.69857
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Rare Presentation of Testicular Cancer With Malignant Tumor Thrombus: A Case Report

Abdulaziz H Khushaym, Noora Aljeeran, Lana Alabbasi
Cureus
Testicular diseases and treatments
article

Rare Presentation of Testicular Cancer With Malignant Tumor Thrombus: A Case Report

Abdulaziz H Khushaym, Noora Aljeeran, Lana Alabbasi
article en

Abstract

In rare cases, testicular cancer can metastasize to the inferior vena cava (IVC) through a tumor thrombus, significantly worsening the prognosis. This case report describes the management and the outcome of a rare presentation of testicular cancer. A 38-year-old male presented with a testicular mass and was found to have a mixed germ cell tumor with predominantly yolk sac components. Imaging after the initial orchiectomy revealed an IVC tumor thrombus extending from the left renal vein, as well as retroperitoneal and pulmonary metastases. The patient was urgently started on anticoagulation and underwent three cycles of BEP chemotherapy (bleomycin, etoposide, and cisplatin), which led to complete metabolic and radiographic regression of the metastatic disease.

CureusVol. 16(9)
King Hamad University Hospital (BH)
Good health and well-being
Openalex Percentile: Top 70%
Testicular diseases and treatments
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