Stimulation of fracture mineralization by salt-inducible kinase inhibitors
YKL-05-099 enhances fracture repair, supporting selective SIK inhibitors' development for clinical use. Hydrogel-based siRNA delivery offers targeted localized treatment at fracture sites.
Authors
- Pere Dosta (ORCID: https://orcid.org/0000-0002-4407-1420)
- Eliz Amar‐Lewis (ORCID: https://orcid.org/0000-0001-9552-9780)
- Marc N. Wein (ORCID: https://orcid.org/0000-0002-6015-8147)
- Mohamed Yousef (ORCID: https://orcid.org/0000-0002-3593-2452)
- Garyfallia Papaioannou (ORCID: https://orcid.org/0000-0002-1743-7474)
- Ara Nazarian (ORCID: https://orcid.org/0000-0003-3992-3489)
- Mohammadreza Abbasian (ORCID: https://orcid.org/0000-0002-7949-8213)
- Diana Yeritsyan
- Nadim Kheir (ORCID: https://orcid.org/0000-0002-0555-6265)
- Jialiang S. Wang (ORCID: https://orcid.org/0000-0002-3409-7619)
- Natalie Artzi
- John J. Wixted (ORCID: https://orcid.org/0000-0002-4297-225X)
- Kaveh Momenzadeh (ORCID: https://orcid.org/0000-0003-1742-358X)
- Edith Martinez Lozano (ORCID: https://orcid.org/0000-0002-3527-2650)
- Cheng-Chia Tang
- Philip Hanna
- S Goldfarb
- Michaela Nicole Prado Larrea
Institutions
- Boston University (US)
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
- Massachusetts General Hospital (US)
- Southwestern Medical Center (US)
- Inspire Institute (US)
- Yerevan State Medical University (AM)
- Massachusetts Institute of Technology (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Frontiers in Bioengineering and Biotechnology
- Published
- 2024-09-16
- DOI
- https://doi.org/10.3389/fbioe.2024.1450611
- Citations
- 2
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- Brigham and Women's Hospital
- Massachusetts General Hospital
- Beth Israel Deaconess Medical Center
- Strong
- National Institutes of Health