Demographic Trends, Co-Alterations, and Imatinib Resistance across Genomic Variants in Gastrointestinal Stromal Tumors: An AACR Project GENIE Analysis
Sex and race/ethnic differences in genomic alterations, as well as co-mutations, were prevalent among patients with GIST. Variations in mutational profiles highlight the importance of distinct genetic drivers that may be targeted to treat different patient populations.
Authors
- Hunter Stecko (ORCID: https://orcid.org/0009-0000-8255-9614)
- Timothy Michael Pawlik (ORCID: https://orcid.org/0000-0002-7994-9870)
- Diamantis I. Tsilimigras
- Sidharth Iyer
Institutions
- The Ohio State University Wexner Medical Center (US)
- The Ohio State University (US)
Publication Details
- Journal
- Oncology
- Published
- 2024-09-21
- DOI
- https://doi.org/10.1159/000541454
- Citations
- 2
- Primary Topic
- Gastrointestinal Tumor Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.93