Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy

Our findings demonstrate that SGD promotes autophagy/mitophagy, which effectively mitigates APAP-induced hepatotoxicity, suggesting SGD's potential as a promising therapeutic agent for APAP-induced liver injury.

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Publication Details

Journal
Phytomedicine
Published
2024-09-21
DOI
https://doi.org/10.1016/j.phymed.2024.156053
Citations
22
Primary Topic
Drug-Induced Hepatotoxicity and Protection
Type
article
Field-Weighted Citation Impact
10.27
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article

Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy

Jinghao Zhang, Yueqiu Gao, Xuehua Sun, Xiaoni Kong et al.
22 citations
Phytomedicine
Drug-Induced Hepatotoxicity and Protection
10.27
article

Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy

Jinghao Zhang, Yueqiu Gao, Xuehua Sun, Xiaoni Kong, Liping You, Wenxuan Li, Chao Zheng, Jiacheng Lin, Yuelan Wu, Jian Su
article en
22 citations

Abstract

Our findings demonstrate that SGD promotes autophagy/mitophagy, which effectively mitigates APAP-induced hepatotoxicity, suggesting SGD's potential as a promising therapeutic agent for APAP-induced liver injury.

PhytomedicineVol. 135
Shanghai University of Traditional Chinese Medicine (CN), Shuguang Hospital (CN)
Good health and well-being
Openalex Percentile: Top 1%
Drug-Induced Hepatotoxicity and Protection
10.27
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Shaoyao-Gancao Decoction, a famous Chinese medicine formula, protects against APAP-induced liver injury by promoting autophagy/mitophagy — Jinghao Zhang, Yueqiu Gao, et al. · Phytomedicine (2024) | TGRS Research Map | TGRS