[Physical, chemical, and biological property of silk reinforced polycaprolactone composites for bone tissue engineering].
SPC has the mechanical and hydrophilic properties that are compatible with bone tissue. It maintains its mechanical strength for a long time in a simulated body fluid environment <i>in vitro</i>, and achieves dynamic synchronization of material degradation, tissue regeneration, and vascularization through the body's immune regulation mechanism <i>in vivo</i>. It is expected to provide a new type of implant material for clinical bone repair.
Authors
- Yuzeng Liu (ORCID: https://orcid.org/0000-0003-2128-4594)
- Guanping He (ORCID: https://orcid.org/0000-0001-9088-5110)
- Juan Guan (ORCID: https://orcid.org/0000-0002-9784-8125)
- Wenhan Tian (ORCID: https://orcid.org/0009-0009-0556-8221)
Institutions
- Beijing Chao-Yang Hospital, Capital Medical University (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
- Beijing Advanced Sciences and Innovation Center (CN)
- Beihang University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-09-15
- DOI
- https://doi.org/10.7507/1002-1892.202404120
- Primary Topic
- Silk-based biomaterials and applications
- Type
- article