Changes of <scp>NLRP3</scp> in serum and cerebrospinal fluid of patients after moderate to severe traumatic brain injury and their predictive values for prognosis
The levels of NLRP3, especially in the CSF on day 3 post-injury, can serve as a potential biomarker for predicting prognosis in moderate to severe TBI patients. Early measurement of NLRP3 levels can provide valuable insights into patient outcomes and guide therapeutic strategies.
Authors
- Guangyao Zhu (ORCID: https://orcid.org/0009-0005-7734-1019)
- Maosong Chen (ORCID: https://orcid.org/0009-0005-3000-9596)
- Pandi Chen (ORCID: https://orcid.org/0009-0007-7332-5008)
- Gengfan Ye (ORCID: https://orcid.org/0000-0002-7298-2571)
- Shufeng Zou (ORCID: https://orcid.org/0000-0001-5950-1676)
- Wei Chen (ORCID: https://orcid.org/0009-0005-4273-5843)
- Hongcai Wang (ORCID: https://orcid.org/0000-0002-3343-7853)
- Shiwei Li
- Zhigang Wang
Institutions
- Ningbo University (CN)
- Nanchang University (CN)
- Ningbo Medical Center Lihuili Hospital (CN)
- Shanghai East Hospital (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- CNS Neuroscience & Therapeutics
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1111/cns.70009
- Citations
- 4
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 1.48
Funders
- National Natural Science Foundation of China
- Ningbo Municipal Bureau of Science and Technology
- Education Department of Jiangxi Province
- Jiangxi Provincial Department of Science and Technology