Body Skin Laxity Treatment Using Hybrid Cooperative Complexes of Hyaluronans: A Real-World Data Evaluation of Patient-Reported Satisfaction

Background:The Profhilo Body Kit is indicated for the treatment of skin laxity of the body and consists of the Profhilo Body hyaluronic acid (HA) injectable, the HA-containing Profhilo Figura Body Patch and the Profhilo Figura Body Cream. Aim:To assess real-world data of patient-reported satisfaction associated with the Profhilo Body Kit treatment for skin laxity of the inner arms, abdomen, dcollet, and knees. Methods:The Profhilo Body injection and Profhilo Figura Body Patch were administered on Day 0 and Day 30; the Profhilo Figura Body Cream was applied daily between the two injections.Surveys were conducted using a web app tool (Day 0, Day 30 and 30-days after second injection) and assessed patient discomfort (Visual Analogue Scale), treatment effectiveness, and psychological and social function (effects assessed using four categories: 'not at all', 'a little', 'a lot' and 'very much').Results: Patients (N=50; 83% female) were treated at centres in Italy (n=35) and in the Netherlands (n=15).Most patients had no/ mild procedure-related pain (86%) and the majority of post-injection symptoms disappeared within 48 hours (94%).Over 80% of patients reported that treatment benefited them 'a lot' and 'very much', with improvements in skin laxity, skin hydration and skin firmness/tone; beneficial treatment effects were also reported for enhancement of body image, appearance and improvement in relationships. Discussion and Conclusions:These results indicate a high-level of patient-reported satisfaction due to the Profhilo Body Kit and this contributes to the growing body of evidence supporting the use of Profhilo Body for the treatment of skin laxity.