Lotus Sprout Extract Induces Selective Melanosomal Autophagy and Reduces Pigmentation
This study revealed a novel mechanism for LSE, neferine, and liensinine in reducing pigmentation, potentially through the induction of autophagy and subsequent melanosome degradation. These findings suggest that LSE and its enriched bioactive compounds could be promising agents for treating hyperpigmentation.
Authors
- Prithwiraj Maitra (ORCID: https://orcid.org/0000-0002-0455-1411)
- Robin Chung
- Rahul Mehta (ORCID: https://orcid.org/0000-0002-7613-5847)
- Kuniko Kadoya (ORCID: https://orcid.org/0000-0002-8758-6635)
- Neil J. Poloso (ORCID: https://orcid.org/0000-0002-8575-4199)
- Mikhail Geyfman (ORCID: https://orcid.org/0000-0002-8813-4710)
- Raymond E. Boissy
Institutions
- AbbVie (United States) (US)
- Allergan (United States) (US)
- University of Cincinnati (US)
Publication Details
- Journal
- Journal of Cosmetic Dermatology
- Published
- 2024-09-21
- DOI
- https://doi.org/10.1111/jocd.16587
- Citations
- 4
- Primary Topic
- melanin and skin pigmentation
- Type
- article
- Field-Weighted Citation Impact
- 1.30