Immunological responses to brain metastasis stereotactic radiosurgery in patient-matched longitudinal blood and tumour samples
Systemic and local immunological changes in this homogenous patient cohort suggest that SRS may facilitate MHC-II-restricted T cell priming responses involving the monocyte-macrophage lineage and CD4+ T cells, which should be further explored.
Authors
- Yukuan Huang (ORCID: https://orcid.org/0000-0003-2262-7069)
- Paul J. Neeson (ORCID: https://orcid.org/0000-0002-2729-5887)
- Metta Jana (ORCID: https://orcid.org/0000-0001-7092-045X)
- Claire Phillips (ORCID: https://orcid.org/0000-0001-7215-8729)
- Joseph Sia (ORCID: https://orcid.org/0000-0002-9056-0903)
- Criselle D’Souza
- Rejhan Idrizi
- Shankar Siva (ORCID: https://orcid.org/0000-0003-2840-0658)
- Han Xiang Aw Yeang
- Becky Castle
Institutions
- Peter MacCallum Cancer Centre (AU)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2024-09-21
- DOI
- https://doi.org/10.1016/j.ctro.2024.100863
- Citations
- 3
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.26
Funders
- Cancer Council Victoria