Favourable humoral but reduced cellular immune response to COVID-19 mRNA BNT162b2 vaccine in patients with childhood-onset systemic lupus erythematosus
Patients with cSLE showed robust humoral but compromised cellular immune responses to the COVID-19 mRNA vaccine, associated with lower lymphocyte counts. These findings highlight the need for further research to enhance vaccine efficacy in this vulnerable group.
Authors
- Rüveyda Gülmez (ORCID: https://orcid.org/0000-0001-5504-3516)
- Ayşe Ağbaş (ORCID: https://orcid.org/0000-0002-3658-8622)
- Aybüke Gunalp (ORCID: https://orcid.org/0000-0003-0137-0460)
- Nur Canpolat (ORCID: https://orcid.org/0000-0002-3420-9756)
- Doğukan Özbey (ORCID: https://orcid.org/0000-0002-0596-1551)
- Salim Çalışkan (ORCID: https://orcid.org/0000-0002-3316-8032)
- Esra Karabağ Yılmaz (ORCID: https://orcid.org/0000-0002-6097-657X)
- Özgür Kasapçopur (ORCID: https://orcid.org/0000-0002-1125-7720)
- Bekir Sami Kocazeybek (ORCID: https://orcid.org/0000-0003-1072-3846)
- Sezgin Şahin (ORCID: https://orcid.org/0000-0002-5365-3457)
- Seha Saygılı (ORCID: https://orcid.org/0000-0002-2424-6959)
Institutions
- Istanbul University-Cerrahpaşa (TR)
Publication Details
- Journal
- Lupus Science & Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1136/lupus-2024-001268
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Istanbul Üniversitesi-Cerrahpasa