Toward Understanding the Anticancer Activity of the Phytocompounds from Eugenia uniflora Using Molecular Docking, in silico Toxicity and Dynamics Studies
This study has shown that polyphenol compounds of <i>E. uniflora</i> led by galloylastragalin, are potent inhibitors of the MDM2 and Bcl-xL cancer proteins. Thus, they may be considered as candidate polyphenols for further anticancer studies.
Authors
- Pallab Kar (ORCID: https://orcid.org/0000-0002-2340-3174)
- Ayodeji O. Oriola (ORCID: https://orcid.org/0000-0002-4166-0449)
- Adebola O. Oyedeji (ORCID: https://orcid.org/0000-0001-8765-7766)
Institutions
- Walter Sisulu University (ZA)
Publication Details
- Journal
- Advances and Applications in Bioinformatics and Chemistry
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/aabc.s473928
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.36