Effects of zuranolone on next-day simulated driving in healthy adults
Zuranolone impaired simulated driving and reduced cognitive function versus placebo 9 h after administration. Although many impairments resolved after 7 days of dosing, driving remained impaired. These results may inform prescriber decision-making.
Authors
- Indrani Nandy
- Seth Levin (ORCID: https://orcid.org/0000-0001-9222-1094)
- Rakesh K. Jain (ORCID: https://orcid.org/0000-0001-7571-3548)
- Victor Ona
- Joi Dunbar (ORCID: https://orcid.org/0009-0004-7663-1535)
- Carrie Vaudreuil (ORCID: https://orcid.org/0000-0002-5971-7554)
- Gaetano Morelli (ORCID: https://orcid.org/0009-0005-8238-8751)
- Gary G. Kay
- Margaret K Moseley
Institutions
- The University of Texas of the Permian Basin (US)
- Texas Tech University (US)
- Biogen (United States) (US)
- Sage Therapeutics (United States) (US)
- ALTA (Italy) (IT)
- Cognitive Research (United States) (US)
Publication Details
- Journal
- Psychopharmacology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1007/s00213-024-06687-6
- Citations
- 3
- Primary Topic
- Sleep and Work-Related Fatigue
- Type
- article
- Field-Weighted Citation Impact
- 1.52
Funders
- Biogen
- Sage Therapeutics