Uterine inflammatory myofibroblastic tumor: a retrospective analysis

Uterine inflammatory myofibroblastic tumor is easily misdiagnosed, making its diagnosis challenging. Histological features, immunohistochemical results, and molecular confirmation using fluorescence <i>in situ</i> hybridization (FISH) or Next-generation sequencing should be used to confirm the diagnosis. Positive ALK immunohistochemistry, ALK rearrangement, ALK fusion are helpful in diagnosis and ALK inhibitor therapy. Total hysterectomy is often performed for women who do not require fertility, while lesion resection and close follow-up may be considered for those who require fertility preservation.

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Publication Details

Journal
Frontiers in Oncology
Published
2024-09-20
DOI
https://doi.org/10.3389/fonc.2024.1461092
Citations
5
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
2.35
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article

Uterine inflammatory myofibroblastic tumor: a retrospective analysis

Liping Bai, Yali Chen, Ai Zheng, Ling Han
5 citations
Frontiers in Oncology
IgG4-Related and Inflammatory Diseases
2.35
article

Uterine inflammatory myofibroblastic tumor: a retrospective analysis

Liping Bai, Yali Chen, Ai Zheng, Ling Han
article en
5 citations

Abstract

Uterine inflammatory myofibroblastic tumor is easily misdiagnosed, making its diagnosis challenging. Histological features, immunohistochemical results, and molecular confirmation using fluorescence <i>in situ</i> hybridization (FISH) or Next-generation sequencing should be used to confirm the diagnosis. Positive ALK immunohistochemistry, ALK rearrangement, ALK fusion are helpful in diagnosis and ALK inhibitor therapy. Total hysterectomy is often performed for women who do not require fertility, while lesion resection and close follow-up may be considered for those who require fertility preservation.

Frontiers in OncologyVol. 14
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN)
Good health and well-being
Openalex Percentile: Top 11%
IgG4-Related and Inflammatory Diseases
2.35
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