DENV Peptides Delivered as Spherical Nucleic Acid Constructs Enhance Antigen Presentation and Immunogenicity in vitro and in vivo
The study demonstrates the successful development of SNA-TBB as a promising nanovaccine platform against DENV infection and highlights the potential of SNA-based peptide vaccines as a strategy for developing safe and effective antiviral immunotherapy.
Authors
- Jintao Li (ORCID: https://orcid.org/0000-0003-3637-2386)
- Xiaoyan Ding (ORCID: https://orcid.org/0000-0002-0741-2708)
- Jiuxiang He
- Hua Dong (ORCID: https://orcid.org/0000-0002-8235-726X)
- Minchi Liu
- Jing Zhao (ORCID: https://orcid.org/0000-0001-8681-3296)
- Xiaozhong Chen (ORCID: https://orcid.org/0000-0003-4351-9753)
- Yuxin Zhou
- Jun Tong
- Wenxuan Quan
Institutions
- Army Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s467427
- Citations
- 3
- Primary Topic
- RNA Interference and Gene Delivery
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- National Natural Science Foundation of China