Protective effect of MP-40 mitigates BDL-induced hepatic fibrosis by inhibiting the NLRP3-mediated pyroptosis
The results proved that MP-40 alleviates BDL-induced cholestatic hepatic fibrosis by inhibiting NLRP3-mediated pyroptosis. PF and TGG play a role in treating BDL-induced cholestatic hepatic fibrosis in MP-40.
Authors
- Minjing Qin
- Xuedong Wan
- Qitong Zheng
- Min Hao (ORCID: https://orcid.org/0000-0003-1007-2254)
- Mengyun Peng (ORCID: https://orcid.org/0000-0001-9324-4204)
- Gang Cao (ORCID: https://orcid.org/0000-0002-0819-0430)
- Xianan Sang (ORCID: https://orcid.org/0000-0001-5511-7220)
- Qiao Yang (ORCID: https://orcid.org/0000-0002-0480-6146)
- Xin Han (ORCID: https://orcid.org/0000-0002-1725-7940)
- Kuilong Wang (ORCID: https://orcid.org/0000-0002-6160-1198)
- Yuanyuan Fang (ORCID: https://orcid.org/0000-0001-9095-6169)
- Yiqing Shi
- Ruihua Zhao
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3389/fphar.2024.1479503
- Citations
- 4
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Zhejiang Chinese Medical University
- Chinese Medicine Research Program of Zhejiang Province