A dietary intervention with conjugated linoleic acid enhances microstructural white matter reorganization in experimental stroke
We aimed to explore the efficacy of a dietary intervention with minimal known side effects that could be accessible to human stroke patients, regardless of the degree of disability, and without the risks associated with aggressive immunomodulatory therapies. Our main findings include improved microstructural reorganization in small infarcts and a reduced inflammatory response of human T cells <i>in vitro</i>.
Authors
- Cornelius Faber (ORCID: https://orcid.org/0000-0001-7683-7710)
- Luisa Klotz (ORCID: https://orcid.org/0000-0001-5439-9633)
- Anna‐Lena Börsch (ORCID: https://orcid.org/0000-0001-9174-8652)
- Mailin Hannah Marie Koecke
- Bastian Maus (ORCID: https://orcid.org/0000-0003-1872-9097)
- Maike Hoppen (ORCID: https://orcid.org/0000-0002-7921-8322)
- Frederike Straeten (ORCID: https://orcid.org/0000-0002-3463-6491)
- Jan‐Kolja Strecker (ORCID: https://orcid.org/0000-0003-1518-6971)
- Ann-Katrin Fleck
- Antje Schmidt‐Pogoda (ORCID: https://orcid.org/0000-0002-0389-6389)
- Gerd Meyer zu Hörste (ORCID: https://orcid.org/0000-0002-4341-4719)
- Carolin Beuker (ORCID: https://orcid.org/0000-0003-3495-0357)
- Jens Minnerup (ORCID: https://orcid.org/0000-0002-0382-5759)
- Birgit Schmeddes
- Louisa Mueller-Miny
- Lucia Härtel
- Tabea Straeten
- Stephanie van Zyl
Institutions
- University of Münster (DE)
- University Hospital Münster (DE)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3389/fneur.2024.1341958
- Citations
- 1
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- Deutsche Forschungsgemeinschaft
- Westfälische Wilhelms-Universität Münster