YTHDF3 modulates the progression of breast cancer cells by regulating FGF2 through m6A methylation
In summary, our study elucidates the role of YTHDF3 as an oncogene in maintaining FGF2 expression in BC cells through an m<sup>6</sup>A-dependent mechanism. Additionally, we provide a potential biomarker panel for prognostic prediction in BC.
Authors
- Tung‐Tien Sun (ORCID: https://orcid.org/0000-0002-6841-1063)
- Z. H. Zhang (ORCID: https://orcid.org/0009-0007-8016-8354)
- Rongfang Gong (ORCID: https://orcid.org/0000-0001-5937-9607)
- Y. X. Zhao (ORCID: https://orcid.org/0000-0002-3084-1033)
- Fang Wen (ORCID: https://orcid.org/0000-0001-9470-4620)
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3389/fcell.2024.1438515
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.17
Funders
- Science and Technology Program of Guizhou Province