Diagnostic values of BALF metagenomic next-generation sequencing, BALF real-time PCR and serum BDG for Pneumocystis jirovecii pneumonia in HIV-infected patients
BALF mNGS and real-time PCR are two powerful techniques for rapid diagnosis of PJP with high specificity and sensitivity. Moreover, the benefit of mNGS is that it may identify other organisms besides PJP and it may benefit proper and prompt treatment.
Authors
- Wenjia Hu (ORCID: https://orcid.org/0000-0001-6738-7535)
- Liping Deng (ORCID: https://orcid.org/0000-0002-4897-7721)
- Liangjun Chen (ORCID: https://orcid.org/0000-0001-6678-7617)
- Yong Xiong (ORCID: https://orcid.org/0000-0003-0678-4064)
- Xiao‐Ping Chen (ORCID: https://orcid.org/0000-0002-5852-9965)
- Qianhui Chen (ORCID: https://orcid.org/0009-0002-6651-9684)
- Qian Du (ORCID: https://orcid.org/0000-0002-5228-1508)
- Yongxi Zhang (ORCID: https://orcid.org/0000-0003-3840-5209)
- Qunqun Jiang
- Pingzheng Mo
- Qinglian Guo
- Zhongwei Zhang (ORCID: https://orcid.org/0009-0004-3909-761X)
Institutions
- Wuhan University (CN)
- Zhongnan Hospital of Wuhan University (CN)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3389/fmicb.2024.1421660
- Citations
- 11
- Primary Topic
- Pneumocystis jirovecii pneumonia detection and treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.25
Funders
- Wuhan University
- Zhongnan Hospital of Wuhan University
- Center for AIDS Research, University of Washington