Venous thromboembolism prophylaxis in operative traumatic brain injury

These findings suggest that initiating VTE pharmacological prophylaxis between 3 and 5 days postsurgery may be safe in operative TBI patients, with the timing dependent on the procedure's invasiveness. The low frequencies of worsening intracranial pathology and VTE support the safety of these proposed timeframes. However, the study's limitations, including its single-center retrospective nature and lack of a standardized protocol, necessitate further research to confirm these findings and establish evidence-based guidelines for VTE pharmacological prophylaxis in operative TBI patients.

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Publication Details

Journal
Surgical Neurology International
Published
2024-09-20
DOI
https://doi.org/10.25259/sni_541_2024
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
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article

Venous thromboembolism prophylaxis in operative traumatic brain injury

Eric Legome, Konstantinos D. Margetis, Jacques Lara‐Reyna, Mert Karabacak et al.
Surgical Neurology International
Venous Thromboembolism Diagnosis and Management
article

Venous thromboembolism prophylaxis in operative traumatic brain injury

Eric Legome, Konstantinos D. Margetis, Jacques Lara‐Reyna, Mert Karabacak, Pemla Jagtiani, Gijong Paik
article en

Abstract

These findings suggest that initiating VTE pharmacological prophylaxis between 3 and 5 days postsurgery may be safe in operative TBI patients, with the timing dependent on the procedure's invasiveness. The low frequencies of worsening intracranial pathology and VTE support the safety of these proposed timeframes. However, the study's limitations, including its single-center retrospective nature and lack of a standardized protocol, necessitate further research to confirm these findings and establish evidence-based guidelines for VTE pharmacological prophylaxis in operative TBI patients.

Surgical Neurology InternationalVol. 15
Mount Sinai Health System (US), University of Illinois Urbana-Champaign (US), Illinois College (US), SUNY Downstate Health Sciences University (US), Neurological Surgery (US), Icahn School of Medicine at Mount Sinai (US)
Good health and well-being
Openalex Percentile: Top 68%
Venous Thromboembolism Diagnosis and Management
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