The Study Of Raised Renal Parameters And Their Effect On Maternal And Foetal Outcome In Preeclampsia

Background: Pregnancy in with raised renal parameters was considered high risk but the degree of this risk is unclear. Hence the present study was done to study the effect of raised renal parameters among women with pre-eclampsia on adverse maternal and fetal outcomes. Methodology: A Case -Control study was conducted among Among 100 patients of Pre-eclampsia,50 patients of Pre-eclampsia with raised renal parameters were included in the study group as cases and 50 matched preeclamptic patients with normal renal parameters were chosen as controls for the study. Matching was done with respect to certain variables like age group, gestational age, gravida and associated co-morbid condition (Pre-Eclampsia) to avoid bias, for a period of one year to study the effect of altered renal function tests on maternal and fetal outcome in preeclampsia. Results: Compared to women in the control group, women in the study group had 3.7 times increased odds of preterm delivery (OR, 3.7; 95% CI, 1.0-15.2) and 2.4 times increased odds of delivery via caesarean section (OR, 2.4; 95% CI, 1.09-5.4). Women in the study group was also associated with two-fold increased odds of low birth weight (OR, 2.1; 95% CI, 0.5-9.6). Raised renal parameters among pre-eclamptic women was not associated with increased risk of maternal death in the present study. Conclusion: Raised / abnormal renal parameters in pregnancy is independently associated with adverse maternal and fetal outcomes when other variables and a comorbid condition (Pre-eclampsia) was controlled by matching.