Extracellular matrix production and oxygen diffusion regulate chemotherapeutic response in osteosarcoma spheroids
This work establishes OS spheroids as a valuable tool for early OS tumor formation investigation and holds potential for novel therapeutic target and prognostic indicator discovery.
Authors
- Katherine H. Griffin (ORCID: https://orcid.org/0000-0003-1207-4624)
- J. Kent Leach (ORCID: https://orcid.org/0000-0002-1673-3335)
- R. Lor Randall (ORCID: https://orcid.org/0000-0002-3660-774X)
- Thomas P. Coonan
- Isabel S. Sagheb
Institutions
- UC Davis Health (US)
- University of California, Davis (US)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1002/cam4.70239
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Foundation for the National Institutes of Health