Three new flavonoid glycosides from the herbaceous stems of <i>Ephedra intermedia</i>
Phytochemical investigation of the <i>n</i>-butanol extracts of the herbaceous stems of <i>Epheda intermedia</i> led to the isolation of eight flavonoids that included three new flavonoid glycosides (<b>1</b>-<b>3</b>) and five previously reported analogues (<b>4</b>-<b>8</b>). Their structures have been identified on the basis of various spectral data. Besides, all the flavonoids were tested <i>in vitro</i> for their ability to inhibit <i>α</i>-glucosidase under the positive control of acarbose, and the results indicated that none of them exhibited significant inhibitory effect on <i>α</i>-glucosidase at 100 μM.
Authors
- Yingjie Niu (ORCID: https://orcid.org/0000-0003-1829-1718)
- Xiaoke Zheng (ORCID: https://orcid.org/0000-0003-3671-231X)
- Xiang-Da Li
- Xinyi Ma
- Xu Chen (ORCID: https://orcid.org/0000-0001-6719-1698)
- Yanling Liu (ORCID: https://orcid.org/0000-0001-8682-6599)
- Di Lu (ORCID: https://orcid.org/0000-0002-3054-6325)
- Yan-Gang Cao (ORCID: https://orcid.org/0000-0002-6744-5974)
- Wei-Sheng Feng
Institutions
- Ministry of Education (KR)
- Henan Bioengineering Technology Research Center (CN)
- First Affiliated Hospital of Henan University (CN)
Publication Details
- Journal
- Natural Product Research
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1080/14786419.2024.2405993
- Citations
- 3
- Primary Topic
- Pharmacology and Obesity Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.34