Possibility of Measuring of Erythrocyte Size Distribution Parameters by Laser Diffractometry of a Blood Smear

We consider the issues of obtaining information about the distribution of red blood cells in size from the scattering pattern of a laser beam on a wet blood smear. Within this article it is assumed to calculate the first three moments of the size distribution. The analytical model of light diffraction by blood smears was developed, as well as numerical experiments for verification suggested approach were carried out. The possibility of calculating average diameter of erythrocyte, width and asymmetry of size distribution by analyzing the angular distribution of light intensity in the diffraction pattern was shown

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Publication Details

Journal
Journal of Biomedical Photonics & Engineering
Published
2024-08-29
DOI
https://doi.org/10.18287/jbpe24.10.040302
Primary Topic
Digital Imaging for Blood Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Possibility of Measuring of Erythrocyte Size Distribution Parameters by Laser Diffractometry of a Blood Smear

Evgeniy G. Tsybrov, Alexander V. Priezzhev, Andrei E. Lugovtsov, Maria S. Lebedeva et al.
1 links
Journal of Biomedical Photonics & Engineering
Digital Imaging for Blood Diseases
article

Possibility of Measuring of Erythrocyte Size Distribution Parameters by Laser Diffractometry of a Blood Smear

Evgeniy G. Tsybrov, Alexander V. Priezzhev, Andrei E. Lugovtsov, Maria S. Lebedeva, S. Yu. Nikitin
article en

Abstract

We consider the issues of obtaining information about the distribution of red blood cells in size from the scattering pattern of a laser beam on a wet blood smear. Within this article it is assumed to calculate the first three moments of the size distribution. The analytical model of light diffraction by blood smears was developed, as well as numerical experiments for verification suggested approach were carried out. The possibility of calculating average diameter of erythrocyte, width and asymmetry of size distribution by analyzing the angular distribution of light intensity in the diffraction pattern was shown

Journal of Biomedical Photonics & EngineeringVol. 10(4)
Lomonosov Moscow State University (RU)
Moscow Center of Fundamental and Applied Mathematics, Ministry of Education and Science of the Russian Federation, Russian Science Foundation
Zero hunger
Openalex Percentile: Top 85%
Digital Imaging for Blood Diseases
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Possibility of Measuring of Erythrocyte Size Distribution Parameters by Laser Diffractometry of a Blood Smear — Evgeniy G. Tsybrov, Alexander V. Priezzhev, et al. · Journal of Biomedical Photonics & Engineering (2024) | TGRS Research Map | TGRS