Graves’ Disease Associated With Pulmonary Hypertension and Cardiac Arrest

Thyrotoxicosis has been associated with several cardiac conditions including atrial fibrillation, congestive heart failure due to left ventricular dysfunction, and cardiomyopathy. However, few cases of ventricular fibrillation as a complication of thyrotoxicosis have been reported. Our case described a 45-year-old male with a history of hypertension and Graves' disease, who presented with 1 week of left-sided chest pain associated with shortness of breath on exertion and occasional palpitations. His workup revealed acute diastolic congestive heart failure secondary to thyrotoxicosis, causing pulmonary hypertension, which led to ventricular fibrillation and cardiac arrest. After being treated with methimazole and metoprolol, the patient's symptoms improved. This case underscores the significance of assertive medical interventions alongside both invasive and non-invasive cardiac procedures. Addressing thyrotoxicosis and ventricular arrhythmia in hyperthyroid patients is crucial to prevent potentially life-threatening complications.

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Publication Details

Journal
Journal of Medical Cases
Published
2024-09-20
DOI
https://doi.org/10.14740/jmc4289
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
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article

Graves’ Disease Associated With Pulmonary Hypertension and Cardiac Arrest

Zoran Lasić, Archana Rajagopal Nair, Aditya Mangla, Suresh P. Jain et al.
Journal of Medical Cases
Pulmonary Hypertension Research and Treatments
article

Graves’ Disease Associated With Pulmonary Hypertension and Cardiac Arrest

Zoran Lasić, Archana Rajagopal Nair, Aditya Mangla, Suresh P. Jain, Mitra Asadi, Sheikh Arshad
article en

Abstract

Thyrotoxicosis has been associated with several cardiac conditions including atrial fibrillation, congestive heart failure due to left ventricular dysfunction, and cardiomyopathy. However, few cases of ventricular fibrillation as a complication of thyrotoxicosis have been reported. Our case described a 45-year-old male with a history of hypertension and Graves' disease, who presented with 1 week of left-sided chest pain associated with shortness of breath on exertion and occasional palpitations. His workup revealed acute diastolic congestive heart failure secondary to thyrotoxicosis, causing pulmonary hypertension, which led to ventricular fibrillation and cardiac arrest. After being treated with methimazole and metoprolol, the patient's symptoms improved. This case underscores the significance of assertive medical interventions alongside both invasive and non-invasive cardiac procedures. Addressing thyrotoxicosis and ventricular arrhythmia in hyperthyroid patients is crucial to prevent potentially life-threatening complications.

Journal of Medical CasesVol. 15(10)
Northwell Health (US), Lenox Hill Hospital (US), Jamaica Hospital (US)
Good health and well-being
Openalex Percentile: Top 71%
Pulmonary Hypertension Research and Treatments
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Graves’ Disease Associated With Pulmonary Hypertension and Cardiac Arrest — Zoran Lasić, Archana Rajagopal Nair, et al. · Journal of Medical Cases (2024) | TGRS Research Map | TGRS