Surgical resection and survival of clear cell renal cancer metastases to the pancreas

Introduction:Pancreas is considered one of the organs most frequently affected by recurrence after nephrectomy secondary to renal cell carcinoma reporting an incidence of 20%, 85% of these occur within the first 3 years.Objective: The objective of the study is to evaluate overall survival and disease-free survival in patients with renal cancer and pancreatic metastases who underwent surgical treatment.Methods: A retrospective cross-sectional study of patients with histological diagnosis of renal cancer associated with pancreatic metastasis was performed and included those treated by pancreatoduodenectomy or distal pancreatectomy during the period 1987-2020.Results: 14 patients with pancreatic metastasis were included.Two groups of patients were obtained: those who underwent pancreatic surgery for metastasis and those who did not undergo surgical procedure.According to the location of the metastasis, 71.4% corresponded to a single location and 28.6% to multiple locations.57.1% underwent Whipple and 42.9% distal pancreatectomy.Survival after the surgical procedure was 1150 days versus 499 days in non-operated patients.Conclusion: Pancreatic metastases due to RCC can be curable, improve morbidity, and increase disease-free survival with surgical treatment.