Oral calcium supplementation versus placebo in mitigating citrate reactions during apheresis: an open-label randomized control trial
The cumulative incidence of citrate-related side effects was less pronounced than in the previous research. This could stem from absence of blinding, and the decision to administer calcium drinks to the untreated group upon symptom detection. Although preemptive oral calcium intake before peripheral blood progenitor cell apheresis is not wholly effective, providing calcium-rich beverages to symptomatic donors may stave off symptom intensification.
Authors
- Nobuharu Fujii (ORCID: https://orcid.org/0000-0002-8043-7768)
- Yoshinobu Maeda (ORCID: https://orcid.org/0000-0003-1634-5487)
- Toshiharu Mitsuhashi (ORCID: https://orcid.org/0000-0001-9940-0570)
- Masaya Abe (ORCID: https://orcid.org/0000-0003-2937-739X)
- Fumio Otsuka (ORCID: https://orcid.org/0000-0001-7014-9095)
- Takumi Kondo (ORCID: https://orcid.org/0000-0002-6395-7913)
- Takuya Fukumi
- Tomohiro Urata (ORCID: https://orcid.org/0000-0002-1718-7110)
- Yuichi Sumii (ORCID: https://orcid.org/0000-0002-3677-8813)
- Keiko Fujii (ORCID: https://orcid.org/0009-0005-7614-2448)
- Maiko Kimura
Institutions
- Okayama University (JP)
- Okayama University Hospital (JP)
Publication Details
- Journal
- Hematology Transfusion and Cell Therapy
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1016/j.htct.2024.06.010
- Citations
- 3
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.07