Central nervous system dissemination in spinal cord astrocytomas: association with H3 K27M mutation
Factors indicative of higher SCA malignancy, such as H3 K27M alteration, higher histopathological grade, Ki-67 index (≥ 10%), and tumor length (≥ 4 segments), were similarly suggestive of higher rates of dissemination. The occurrence of dissemination is closely associated with the outcome events in patients with SCA.
Authors
- Ruichao Chai (ORCID: https://orcid.org/0000-0003-3451-8871)
- Wenqing Jia (ORCID: https://orcid.org/0000-0003-2893-9784)
- Lin Han (ORCID: https://orcid.org/0000-0002-7398-0199)
- Yongzhi Wang (ORCID: https://orcid.org/0000-0003-0073-5536)
- Songyuan An
- Yun Liu (ORCID: https://orcid.org/0009-0009-3681-4843)
- Hao Yan (ORCID: https://orcid.org/0000-0001-7911-338X)
- Bo Pang (ORCID: https://orcid.org/0000-0002-0323-5484)
- Yaowu Zhang
- Long Wang (ORCID: https://orcid.org/0000-0003-2173-3505)
- Yilin Wu
Institutions
- Capital Medical University (CN)
- Beijing Tian Tan Hospital (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- Journal of Neurosurgery Spine
- Published
- 2024-09-21
- DOI
- https://doi.org/10.3171/2024.6.spine24233
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.88