Reimagining global health scholarship to tackle health inequities

•Significant health inequities persist between and within countries, necessitating a paradigm shift in global health scholarship.•Building on the contributions global health experts, this article proposes four key considerations for reframing global health scholarship.•This requires deeper engagement with macrosocial drivers of health and the application of population health science principles.•An evolving field also necessitates innovation in data sources, multidisciplinary engagement, expanded analytical tools, and diverse global perspectives.