Optimal treatment strategy for low-grade spinal cord astrocytoma: a retrospective, multicenter analysis by the Neurospinal Society of Japan
The optimal treatment for spinal cord astrocytoma is maximal tumor resection without neurological impairment. When some tumor remains in patients with an MIB-1 SI less than 4.0%, a wait-and-see approach is optimal. If the MIB-1 SI is higher than 4.0%, local radiation therapy is recommended. Adjuvant chemotherapy is not recommended for the treatment of grade II spinal cord astrocytoma.
Authors
- Daisuke Umebayashi (ORCID: https://orcid.org/0000-0001-8797-9546)
- Jun Muto (ORCID: https://orcid.org/0000-0003-4620-2073)
- Seiji Shigekawa (ORCID: https://orcid.org/0009-0005-2884-1201)
- Ryo Kanematsu (ORCID: https://orcid.org/0000-0002-6390-2330)
- Takeharu Kunieda
- Tomoo Inoue (ORCID: https://orcid.org/0000-0001-5131-4307)
- Akihiro Inoue (ORCID: https://orcid.org/0000-0002-7438-2369)
- Masaki Mizuno (ORCID: https://orcid.org/0000-0002-1761-344X)
- Takafumi Mitsuhara (ORCID: https://orcid.org/0000-0003-0523-0107)
- Kazutoshi Hida (ORCID: https://orcid.org/0000-0003-4789-8375)
- Toshiki Endo
- Karl J. Friston
Institutions
- Hiroshima University (JP)
- Fujita Health University (JP)
- Mie University (JP)
- Sapporo Azabu Neurosurgical Hospital (JP)
- Fujieda Municipal General Hospital (JP)
- Saitama Red Cross Hospital (JP)
- Ehime University (JP)
- Tohoku Medical and Pharmaceutical University (JP)
Publication Details
- Journal
- Journal of Neurosurgery Spine
- Published
- 2024-09-21
- DOI
- https://doi.org/10.3171/2024.5.spine24457
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.44