Canagliflozin and iron metabolism in the CREDENCE trial

Iron deficiency is highly prevalent in patients with type 2 diabetes and CKD. Canagliflozin increased TIBC and decreased ferritin in patients with type 2 diabetes and CKD, suggesting increased iron utilization, and improved hemoglobin levels and clinical outcomes regardless of iron deficiency.

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Publication Details

Journal
Nephrology Dialysis Transplantation
Published
2024-09-20
DOI
https://doi.org/10.1093/ndt/gfae198
Citations
3
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
1.07

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article

Canagliflozin and iron metabolism in the CREDENCE trial

Brendon Lange Neuen, Carol A. Pollock, Michael K. Hansen, Niels Jongs et al.
3 citations
Nephrology Dialysis Transplantation
Diabetes Treatment and Management
1.07
article

Canagliflozin and iron metabolism in the CREDENCE trial

Brendon Lange Neuen, Carol A. Pollock, Michael K. Hansen, Niels Jongs, Akihiko Koshino, Hiddo J.L. Heerspink, Stephan J. L. Bakker, Kenneth W. Mahaffey, Clare Arnott, Bruce Charles Neal, Sunil V. Badve, Takashi Wada, Meg Jardine, Vlado Perkovic
article en
3 citations

Abstract

Iron deficiency is highly prevalent in patients with type 2 diabetes and CKD. Canagliflozin increased TIBC and decreased ferritin in patients with type 2 diabetes and CKD, suggesting increased iron utilization, and improved hemoglobin levels and clinical outcomes regardless of iron deficiency.

Nephrology Dialysis TransplantationVol. 40(4)
Kanazawa University (JP), The University of Sydney (AU), University Medical Center Groningen (NL), Kanazawa Medical University (JP), University of Groningen (NL), Royal Prince Alfred Hospital (AU), Royal North Shore Hospital (AU), Concord Repatriation General Hospital (AU), UNSW Sydney (AU), Kanazawa University Hospital (JP), The George Institute for Global Health (AU), St George Hospital (AU), Janssen (United States) (US), Center for Clinical Research (United States) (US), St. George Hospital (IN), George Institute for Global Health (CN), National Health and Medical Research Council (AU), Imperial College London (GB), Stanford University (US)
Janssen Research and Development
Good health and well-being
Openalex Percentile: Top 20%
Diabetes Treatment and Management
1.07
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